This page discuss Linux related parameters for Performance tuning.

Huge Pages 

In case you are running HPC Applications, make sure that huge pages are enabled in order to help cache hit rate, and less memory swaps. In most Linux versions, huge pages is enabled by default.

To check if huge pages are enabled check the following:

$ cat /sys/kernel/mm/redhat_transparent_hugepage/enabled
[always] madvise never

$ cat /sys/kernel/mm/transparent_hugepage/enabled
[always] madvise never